Police have said the King Edward Road in Onchan is now reopen after earlier closing it because of ice.
A chilly start to the day had lead to problems on the roads during Thursday morning's rush hour.
Earlier, a number of vehicles were unable to move in the area of the Whitebridge dip in Onchan.
The following roads still remain closed after Tuesday's snow:
A18 Mountain Road (Ramsey to Creg Ny Baa)
A14 Tholt Y Will Road
B10 Beinney Phott Road (Brandywell Cottage to Mountain Road)
Creg Ny Baa Back Road (Creg Ny Baa to Lonan Church Rd).
These orders are in place until 4.30pm.
A police spokesperson said: 'Please take care when you are out and about, leave plenty of space to the vehicle in front, and leave yourself plenty of time to get to your destination.'
A yellow weather warning for wintry showers and ice is in place until 10am.